PHILADELPHIA NEGATIVE MPNS, MDS/MPNS AND MDS IN THE CONTEXT OF RECENT WHO CHANGES AND INCLUSION OF MOLECULAR SIGNATURES INTO PROGNOSTIC TOOLS: A SINGLE CENTRE EXPERIENCE

Philadelphia Negative MPNs, MDS/MPNs and MDS in the Context of Recent WHO Changes and Inclusion of Molecular Signatures into Prognostic Tools: A Single Centre Experience

Introduction: The fifth edition of WHO classification of myeloid neoplasms has introduced major changes in the defining criteria and grouping of MDS, MDS/MPNs and MPNs.Recently published literature has also cited the importance of new risk-scoring systems by integrating genomic profiling with hematologic and cytogenetic characteristics, in order to

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Three-body anisotropic dynamo: the rotor, the gap and the stator

Following the success of the experimental Fury dynamo [1], we are studying (i) the possibility of a new experiment with the same geometry and the same anisotropic electrical conductivity, but with a wider galinstan gap between Selenium the rotor and the stator than in Fury, in order to allow richer dynamics via Lorentz forces.Of course, to do this,

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A microanatomical and histological study of the postcranial dermal skeleton of the Devonian actinopterygian Cheirolepis canadensis

The Devonian stem-actinoterygian Cheirolepis canadensis is potentially important to understand the evolution of the dermal skeleton of osteichthyans, but the last detailed histological study on this taxon was published more than forty years ago.Here, we present new data about the morphology and the histological structure of scales, fulcra, and fin-

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A real-world demonstration of machine learning generalizability in the detection of intracranial hemorrhage on head computerized tomography

Abstract Machine learning (ML) holds great promise in transforming healthcare.While published studies have shown the utility of ML models in interpreting medical imaging examinations, these are often evaluated under laboratory settings.The importance of real world evaluation is best illustrated by case studies that have documented Upholstered Arm C

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Increasing Extractable Work in Small Qubit Landscapes

An interesting class of physical systems, including those associated with life, demonstrates the ability to hold thermalization at bay and perpetuate states of high free-energy compared to a local environment.In this work we study quantum systems with no external sources or sinks for energy, heat, work, or entropy that allow for high free-energy su

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